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As ARBs are more expensive and have not shown any additional clinical benefits over ACE inhibitors, they are usually considered as an alternative for ACE inhibitors intolerant patients.ACE inhibitors and ARBs share most indications and contraindications:De Sutter J, Mendes M, Franco OH. 2016 European Guidelines on cardiovascular disease prevention in clinical practice The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts). Medications involved in switch therapy include antibiotics, analgesics, antipsychotics, and antivirals.Equivalent Dose & Drug Conversions / Transfers / Switching Angiotensin converting enzyme inhibitors (ACE inhibitors) and angiotensin II receptor blockers (ARBs) ACE inhibitors and ARBs, a cornerstone in the prevention and treatment of cardiovascular disease 30 Jun 2017 Dr. Roberto Martín Asenjo Prof. Hector Bueno , FESC Dr. Michael Mcintosh ACE inhibitors and ARBs act by blocking RAAS with beneficial effects on patients with … Eur Heart J 2016; 37: 2315–2381.De Lorenzo A. The ESC Textbook of Preventive Cardiology. Equivalent Doses Of Ace Inhibitors Chart. When indicated, they should be started at low dose and increased gradually to reach the target dose. HRT is now referred to as Menopausal Hormone Therapy (MHT). ACE inhibitors and Angiotensin II Receptor Blockers (ARBS) continued on page 2 The Formulary ACE-I is ramipril.

Chapter 19 Cardioprotective drugs. HRT is now referred to as Menopausal Hormone Therapy (MHT). Equivalent dosages – Listed by drug class: ACE-Inhibitors: Angiotension II Receptor Blockers (ARBs) Benzodiazepine Dose Conversions : Beta Blockers: HMG – CoA Reductase Inhibitors (Statins) Proton Pump Inhibitors – PPIs: More to come….. ACE inhibitors dosages for hypertension Name Equivalent daily dose Start Usual Maximum Benazepril: 10mg: 10mg: 20–40mg: 80mg Captopril: 50&mg (25mg bid) 12.5–25mg bid-tid

For non-formulary ARBs, an auto-substitution is considered mandatory for indications of hypertension. The conversion data is adapted from Goodman and Gilman’s The Pharmacological Basis of Therapeutics, 9th ed.Corticosteroid Converter – based on anti-inflammatory potencyDose equivalence for commonly used inhaled corticosteroid inhalersFrom the literature, prednisolone 5mg is approximately equivalent to hydrocortisone 20mg in terms of equivalent anti-inflammatory dose.Topical corticosteroids range in potency from mild (class VII) to superpotent (class I— Relative Potency of Selected Topical Corticosteroids).

This section features links to a wide range of clinical resources on equivalent doses and conversions for opioids, benzodiazepines, antidepressants, antipsychotics, corticosteroids and more. Chapter 8: Drugs used in acute cardiovascular care. The Formulary ARBs are valsartan, losartan, and candesartan. While intravenous medications may be more bioavailable and have greater effects, some oral drugs produce serum levels comparable to those of the parenteral form.

Selection of which … We create and share clinical content that is accessible, engaging and concise. United Kingdom: Oxford University Press, 2016.Piepoli MF, Hoes AW, Agewall S, et al. Therefore, the table only contains the most commonly used antidepressants.The goal of this switching table is to offer a guide for physician and pharmacist in switching antipsychotics. The intention of this sheet is to help physicians change their patients to higher or lower approximate doses of MHT if needing to tailor therapy, or remain within the same approximate dose if needing to change brands of MHT.This updated Medicines Q&A gives suggested dose conversions from oral pyridostigmine or neostigmine to parenteral neostigmine and includes example dose conversion calculationsSwitching from intravenous (IV) to oral (PO) therapy as soon as patients are clinically stable can reduce the length of hospitalization and lower associated costs.

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