For this reason, high-dose corticosteroids are required immediately to control disease and, later, the immunosuppressant allows minimisation of the steroid dosage. 02 Sep 2020

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But side effects can include weight gain, GI issues, mood swings, and a handful of … Bacterial infections, such as urinary and respiratory infections, are the most common.

Critically ill patients with these diseases will often relapse unless a dose of around 120 mg/day is given.
These patients, on completing treatment with intravenous methylprednisolone, need high doses of oral prednis(ol)one (usually 1-2 mg/kg body weight).