Specifically, in a study involving 15% AzA, waiting until after moisturizing seemed to result in greater penetration of AzA in all moisturizers tested Topical sulfur is another option, though hard to find and frequently found in masks and other short-contact products.

Mandelic and lactic acid are especially gentle forms of AHAs due to their larger molecules that penetrate slower and may allow some people to use AHAs when they otherwise wouldn’t be able to.To start, add them to your routine on your off-nights and work up tolerability from there. Avoid using other skin medications that contain sulfur, resorcinol, or salicylic acid (common in … :p With that said, remember that the longer you use differin the better your skin will become! To quote a journal that overviews the many OTC treatments for acne:The journal goes on to add: “Unfortunately, lower concentrations of salicylic acid may provide only a modest desmolytic [the process of breaking down carbon-to-carbon double bonds, such as between skin cells] activity, thus producing minimal therapeutic effects.” In shorter terms, your mileage may vary.Over the counter formulations can appear in 0.05% to 5%, while higher concentrations of SA are reserved for prescriptions and chemical peels.These features make it less ideal (and much less studied) than BP for combination therapy with Differin, especially in lower percentages or untested formulations, but for some it may prove useful or even better than BP.To use it with Differin, look for unscented washes or leave-on applications and use on clean, moisturized skin, before applying Differin or every-other-night, when not using Differin. While frequently considered as the oil-friendly version of AHA, it differs from AHAs in how it exfoliates the skin (desquamation, keratolytic) as well as it’s ability to prevent the formation of comedones (comedolytic). Garden of Wisdom is another option, especially for people sensitive to many ingredients. Below is a chart using the information given by Deciem on their regimen page.

Use after removing makeup, following the directions on the bottle, and immediately apply your moisturizer to prevent TEWL. But many drugs can interact with each other.

It is helpful in nearly all cases of acne. I’ve decided I’m going experiment with salicylic acid peels in the coming months, so I’ll be stopping differin in the meantime. However, I want to mention that this formula contains two oils, which may inhibit some of it’s efficacy. Avoid creams or lotions that contain alpha hydroxy or glycolic acids.It may take several weeks before your acne improves, and it may get slightly worse for a short time when you first start using Differin. Do not use this medicine on sunburned, windburned, dry, chapped, irritated, or broken skin. Not recommended. but the only problem is after my face dries once i wash it, it is very, very dry.

Apply your moisturizer while skin is still damp to prevent TEWL (trans-epidermal water loss) and let dry completely before applying a thin layer of Differin (about 20 minutes, if you are using it on the same day you use Differin).To use a benzoyl peroxide cleanser, follow the instructions on the bottle, after removing any sunscreen and makeup with an oil-cleanser.

Do not apply any other skin products unless your doctor has told you to.Avoid getting this medicine in your eyes, nose, or mouth.You may use a skin moisturizer if your skin becomes dry while using Differin.

and I love it. Ive had great results so far, and ive been with it for a week or so, i havent had any new breakouts.