To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.Examples of drugs that can cause interactions with cephalexin are listed below.Cephalexin can cause a severe allergic reaction. Cephalexin for oral suspension* USP (a strawberry flavored formula) is supplied as follows: 125 mg/5 mL: Bottles of 100 mL (NDC 68071-2246-0) Directions for mixing are included on the label. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. The usual dose is 250 mg taken every 6 hours, or a dose of 500 mg every 12 hours may be given. IF AN ALLERGIC REACTION TO CEPHALEXIN OCCURS, DISCONTINUE THE DRUG. Cephalexin is excreted in the urine by glomerular filtration and tubular secretion. Some may be better suited for you than others. If they’re more severe or don’t go away, talk to your doctor or pharmacist.Call your doctor right away if you have serious side effects.
Serious side effects and their symptoms can include the following:Cephalexin oral capsule can interact with other medications, To help avoid interactions, your doctor should manage all of your medications carefully. Meticulously monitor and maintain, within acceptable limits, the patient’s vital signs, blood gases, serum electrolytes, etc. If this occurs, patients should contact their physician as soon as possible.In healthy subjects given single 500 mg doses of cephalexin and metformin, plasma metformin mean CAlthough not observed in this study, adverse effects could potentially arise from coadministration of cephalexin and metformin by inhibition of tubular secretion via organic cationic transporter systems.
This raises your risk of side effects. If other symptoms are present, it is probably secondary to an underlying disease state, an allergic reaction, or toxicity due to ingestion of a second medication.To obtain up-to-date information about the treatment of overdose, a good resource is your certified Regional Poison Control Center. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup.
If an allergic reaction to cephalexin occurs, the drug should be discontinued and the patient treated with the usual agents (e.g., epinephrine or other pressor amines, antihistamines, or corticosteroids).Prolonged use of cephalexin may result in the overgrowth of nonsusceptible organisms. Cephalexin also comes as a tablet or liquid suspension that you take by mouth. When cephalexin capsules, cephalexin for oral suspension, or cephalexin tablets are prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.Cephalexin is contraindicated in patients with known allergy to the cephalosporin group of antibiotics.There is some clinical and laboratory evidence of partial cross-allergenicity of the penicillins and the cephalosporins. Safeguard the patient’s airway when employing gastric emptying or charcoal.Forced diuresis, peritoneal dialysis, hemodialysis, or charcoal hemoperfusion have not been established as beneficial for an overdose of cephalexin; however, it would be extremely unlikely that one of these procedures would be indicated.The oral median lethal dose of cephalexin in rats is > 5000 mg/kg.The adult dosage ranges from 1 to 4 g daily in divided doses. If you do not have a dose-measuring device, ask your pharmacist for one. Your doctor will write the number of refills authorized on your prescription.Your doctor may do blood tests to check how well your kidneys are working. If you have a severe infection, your doctor may give you a larger dose.1–4 grams per day taken in divided doses. No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out.This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Under such conditions, careful clinical observation and laboratory studies should be made because safe dosage may be lower than that usually recommended.Indicated surgical procedures should be performed in conjunction with antibiotic therapy.Broad-spectrum antibiotics should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis.Cephalosporins may be associated with a fall in prothrombin activity.
Standard cephalothin powder should provide the following MIC values:Quantitative methods that require measurement of zone diameters also provide reproducible estimates of the susceptibility of bacteria to antimicrobial compounds.